5/22/2025
Last update
5/22/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.3
USERS' SCORE
Moderately Good
Based on 11 Reviews
7.9
Supplement Facts
Serving Size: 2 Veggie Capsules
Amount Per Serving
%DV
Lutein (from 40mg OptiLut® lutein esters extracted from marigold flower, (Tagetes erecta))
20 mg
†
Trans-Zeaxanthin (from OptiLut® marigold flower ext., (Tagetes erecta))
2 mg
†
Top Medical Research Studies
8
We explored the relationship between serum levels of carotenoids, like lutein, and cardiovascular-kidney-metabolic syndrome in over 1,600 U.S. adults. Through extensive analysis, we found that higher lutein levels corresponded with a lower likelihood of advanced CKM syndrome. Other carotenoids also showed similar protective effects, but β-cryptoxanthin did not demonstrate any significant benefit. This suggests that increasing intake of carotenoids, especially lutein, may be a smart choice for heart health.
Read More
8
We aimed to investigate how levels of certain carotenoids impact mortality rates in adults with metabolic dysfunction-associated fatty liver disease (MAFLD). Our analysis involved over 3,000 participants and focused on deaths from all causes, including cardiovascular issues.
Interestingly, higher levels of lutein and other carotenoids correlated with a lower risk of death. Specifically, those with the highest lutein levels were 38% less likely to die from cardiovascular disease compared to those with the lowest levels. However, it's important to note that while the correlation exists, we cannot definitively claim that lutein directly prevents heart disease based on this study alone.
Interestingly, higher levels of lutein and other carotenoids correlated with a lower risk of death. Specifically, those with the highest lutein levels were 38% less likely to die from cardiovascular disease compared to those with the lowest levels. However, it's important to note that while the correlation exists, we cannot definitively claim that lutein directly prevents heart disease based on this study alone.
Read More
8
Supplementation reduces inflammation markers
In our double-blind, placebo-controlled study, we assessed the effects of lutein, zeaxanthin, and meso-zeaxanthin on cardiovascular inflammation and oxidative processes. Participants received either the active supplement or a placebo for six months.
We found significant reductions in key inflammatory markers and oxidized LDL in those taking the supplement. These results suggest that lutein and its companions may help combat inflammation, potentially contributing to healthier cardiovascular systems by supporting lower levels of harmful lipid oxidation.
We found significant reductions in key inflammatory markers and oxidized LDL in those taking the supplement. These results suggest that lutein and its companions may help combat inflammation, potentially contributing to healthier cardiovascular systems by supporting lower levels of harmful lipid oxidation.
Read More
Most Useful Reviews
7.5
Eased eye strain
15 people found this helpful
Due to severe dry eye and presbyopia, I struggled to read small letters, particularly at morning. After taking lutein, I noticed a significant reduction in discomfort, and clearer vision emerged soon after. Initially sceptical, I was pleasantly surprised as eye strain symptoms eased, allowing me to read effortlessly. This supplement has made a noticeable difference in my day-to-day activities, leading me to commit to its ongoing use. I’m grateful for finding this wonderful product.
Read More
9
Improved eye health
4 people found this helpful
Since incorporating Lutein into my routine, my eye health has substantially improved. Symptoms of dryness have decreased, and the light sensitivity I previously experienced has lessened. This supplement plays a crucial role in preventing potential eye diseases. I believe it’s essential for anyone concerned about maintaining their eyesight to consider Lutein.
Read More
9
Reduced eye aging
1 people found this helpful
Since I began taking this product, focusing my eyes has become much easier. Lutein is prevalent in the macula and crystalline lens; a deficiency can lead to eye aging, such as macular degeneration and cataracts. As an antioxidant, lutein combats "active oxygen," which accelerates eye aging, absorbing harmful light and providing protection. It's recommended to take at least 6 mg daily, with a continuous intake of 10 mg reducing the risk of age-related eye diseases. Although it's late for treating my current condition, I will continue to purchase it.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.3
- All Researches
9
We explored the potential of lutein, a powerful antioxidant, in treating myocardial ischemia-reperfusion injury. To enhance its effectiveness, a novel delivery system named lutein@DTPP was developed, allowing for targeted administration directly to heart tissues.
Our findings showed that this method improved mitochondrial function in heart cells, crucial for reducing damage and preventing cell death. However, while lutein demonstrated benefits in this context, it's important to note that the study primarily focused on a specific injury model, and broader effects on cardiovascular disease might still require more investigation.
Our findings showed that this method improved mitochondrial function in heart cells, crucial for reducing damage and preventing cell death. However, while lutein demonstrated benefits in this context, it's important to note that the study primarily focused on a specific injury model, and broader effects on cardiovascular disease might still require more investigation.
Read More
8
We explored the relationship between serum levels of carotenoids, like lutein, and cardiovascular-kidney-metabolic syndrome in over 1,600 U.S. adults. Through extensive analysis, we found that higher lutein levels corresponded with a lower likelihood of advanced CKM syndrome. Other carotenoids also showed similar protective effects, but β-cryptoxanthin did not demonstrate any significant benefit. This suggests that increasing intake of carotenoids, especially lutein, may be a smart choice for heart health.
Read More
8
We aimed to investigate how levels of certain carotenoids impact mortality rates in adults with metabolic dysfunction-associated fatty liver disease (MAFLD). Our analysis involved over 3,000 participants and focused on deaths from all causes, including cardiovascular issues.
Interestingly, higher levels of lutein and other carotenoids correlated with a lower risk of death. Specifically, those with the highest lutein levels were 38% less likely to die from cardiovascular disease compared to those with the lowest levels. However, it's important to note that while the correlation exists, we cannot definitively claim that lutein directly prevents heart disease based on this study alone.
Interestingly, higher levels of lutein and other carotenoids correlated with a lower risk of death. Specifically, those with the highest lutein levels were 38% less likely to die from cardiovascular disease compared to those with the lowest levels. However, it's important to note that while the correlation exists, we cannot definitively claim that lutein directly prevents heart disease based on this study alone.
Read More
8
Supplementation reduces inflammation markers
In our double-blind, placebo-controlled study, we assessed the effects of lutein, zeaxanthin, and meso-zeaxanthin on cardiovascular inflammation and oxidative processes. Participants received either the active supplement or a placebo for six months.
We found significant reductions in key inflammatory markers and oxidized LDL in those taking the supplement. These results suggest that lutein and its companions may help combat inflammation, potentially contributing to healthier cardiovascular systems by supporting lower levels of harmful lipid oxidation.
We found significant reductions in key inflammatory markers and oxidized LDL in those taking the supplement. These results suggest that lutein and its companions may help combat inflammation, potentially contributing to healthier cardiovascular systems by supporting lower levels of harmful lipid oxidation.
Read More
8
Our analysis focused on how carotenoid intake relates to abdominal aortic calcification (AAC), a crucial indicator of cardiovascular risk. In a study with 2,889 participants, we found that increased consumption of carotenoids—particularly lutein and zeaxanthin—was linked to a reduced risk of severe AAC.
Results showed that higher intakes of various carotenoids, including lutein, significantly lowered the odds of AAC, emphasizing the potential heart health benefits of these nutrients. This suggests that including more carotenoid-rich foods in our diet might be beneficial for our cardiovascular health.
Results showed that higher intakes of various carotenoids, including lutein, significantly lowered the odds of AAC, emphasizing the potential heart health benefits of these nutrients. This suggests that including more carotenoid-rich foods in our diet might be beneficial for our cardiovascular health.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 11 Reviews
7.9
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Eased eye strain
15 people found this helpful
Due to severe dry eye and presbyopia, I struggled to read small letters, particularly at morning. After taking lutein, I noticed a significant reduction in discomfort, and clearer vision emerged soon after. Initially sceptical, I was pleasantly surprised as eye strain symptoms eased, allowing me to read effortlessly. This supplement has made a noticeable difference in my day-to-day activities, leading me to commit to its ongoing use. I’m grateful for finding this wonderful product.
Read More
9
Improved eye health
4 people found this helpful
Since incorporating Lutein into my routine, my eye health has substantially improved. Symptoms of dryness have decreased, and the light sensitivity I previously experienced has lessened. This supplement plays a crucial role in preventing potential eye diseases. I believe it’s essential for anyone concerned about maintaining their eyesight to consider Lutein.
Read More
9
Reduced eye aging
1 people found this helpful
Since I began taking this product, focusing my eyes has become much easier. Lutein is prevalent in the macula and crystalline lens; a deficiency can lead to eye aging, such as macular degeneration and cataracts. As an antioxidant, lutein combats "active oxygen," which accelerates eye aging, absorbing harmful light and providing protection. It's recommended to take at least 6 mg daily, with a continuous intake of 10 mg reducing the risk of age-related eye diseases. Although it's late for treating my current condition, I will continue to purchase it.
Read More
7.5
Stabilised retinal condition
37 people found this helpful
My mother, aged over 65, has lived with retinal dystrophy for many years. She consistently takes Lutein for her eyesight, reportedly achieving better twilight vision, colour distinction, and overall eye comfort. We consume 30-40 mg daily to halt disease progression, as she claims her eyes feel less strained, and her mind feels clearer in the mornings. This natural carotenoid has proven essential, thus we remain committed to its use, hoping it will help prolong her vision health. Eye health matters immensely and should not be neglected.
Read More
5
Recommending for prevention
3 people found this helpful
The quality of this lutein product is commendable, and I will repurchase it if needed. This carotenoid helps enhance dark adaptation, filters harmful blue light, and improves overall visual function. Its protective properties support prevention against macular degeneration and cataracts, making it an essential supplement for eye health. Importantly, it also contributes to reducing the risk of cardiovascular disease, making it beneficial for overall wellbeing.
Read More
Frequently Asked Questions
7.5
Rapid eyesight improvement
1 people found this helpful
My eyesight improved significantly after just a week of taking this supplement. The clarity with which I can read signs outside is remarkable. Committed to continuing this regimen, I see it as a vital step in preventing eye diseases.
7.5
Improved eye comfort
5 people found this helpful
To alleviate eye fatigue and enhance vision clarity, Lutein is indispensable. This carotenoid isn't produced naturally in the body and must come from food or supplements. It aids in optimising visual perception and accelerates cell recovery. I experienced significant improvement in my symptoms, including alleviated discomfort and headaches, since I started taking Lutein, although I recommend an initial higher dosage before transitioning to a maintenance dose over two months. This supplement additionally supports the immune system by activating T-lymphocytes providing both antitumor and antiviral protection. Thus, while it isn’t a cure for existing eye diseases, it certainly plays a preventive role.
9
Improved eye health
4 people found this helpful
Since incorporating Lutein into my routine, my eye health has substantially improved. Symptoms of dryness have decreased, and the light sensitivity I previously experienced has lessened. This supplement plays a crucial role in preventing potential eye diseases. I believe it’s essential for anyone concerned about maintaining their eyesight to consider Lutein.
7.5
Eased eye strain
15 people found this helpful
Due to severe dry eye and presbyopia, I struggled to read small letters, particularly at morning. After taking lutein, I noticed a significant reduction in discomfort, and clearer vision emerged soon after. Initially sceptical, I was pleasantly surprised as eye strain symptoms eased, allowing me to read effortlessly. This supplement has made a noticeable difference in my day-to-day activities, leading me to commit to its ongoing use. I’m grateful for finding this wonderful product.
7.5
Improved eye health
1 people found this helpful
After my father took it, his dry eye condition has improved significantly. Lutein boasts several proven benefits, including supporting brain health in the elderly, mitigating retinopathy of prematurity, and enhancing cognitive function. It is also beneficial for age-related macular degeneration, bone health, and dark adaptation. Furthermore, it promotes physical activity, benefits diabetic retinopathy, and boosts stress resistance. Notably, lutein is recognised for its role in preventing cardiovascular disease and metabolic diseases while improving visual adaptability and reducing the likelihood of cataracts.
5
Recommending for prevention
3 people found this helpful
The quality of this lutein product is commendable, and I will repurchase it if needed. This carotenoid helps enhance dark adaptation, filters harmful blue light, and improves overall visual function. Its protective properties support prevention against macular degeneration and cataracts, making it an essential supplement for eye health. Importantly, it also contributes to reducing the risk of cardiovascular disease, making it beneficial for overall wellbeing.
9
Reduced eye aging
1 people found this helpful
Since I began taking this product, focusing my eyes has become much easier. Lutein is prevalent in the macula and crystalline lens; a deficiency can lead to eye aging, such as macular degeneration and cataracts. As an antioxidant, lutein combats "active oxygen," which accelerates eye aging, absorbing harmful light and providing protection. It's recommended to take at least 6 mg daily, with a continuous intake of 10 mg reducing the risk of age-related eye diseases. Although it's late for treating my current condition, I will continue to purchase it.
7.5
Stabilised retinal condition
37 people found this helpful
My mother, aged over 65, has lived with retinal dystrophy for many years. She consistently takes Lutein for her eyesight, reportedly achieving better twilight vision, colour distinction, and overall eye comfort. We consume 30-40 mg daily to halt disease progression, as she claims her eyes feel less strained, and her mind feels clearer in the mornings. This natural carotenoid has proven essential, thus we remain committed to its use, hoping it will help prolong her vision health. Eye health matters immensely and should not be neglected.
8
We examined the effects of serum carotenoids, specifically lutein, on cardiovascular disease (CVD) risk using a robust data set from the National Health and Nutrition Examination Survey.
Our analysis of over 12,000 participants revealed that higher levels of lutein were linked to a lower prevalence of CVD, including a significant reduction in risks of heart attack and stroke.
Although lutein shows promise, it’s essential to remember that these findings indicate correlation, not causation, and we can't say for certain that lutein directly prevents heart disease.
Our analysis of over 12,000 participants revealed that higher levels of lutein were linked to a lower prevalence of CVD, including a significant reduction in risks of heart attack and stroke.
Although lutein shows promise, it’s essential to remember that these findings indicate correlation, not causation, and we can't say for certain that lutein directly prevents heart disease.
8
Supplementation reduces inflammation markers
In our double-blind, placebo-controlled study, we assessed the effects of lutein, zeaxanthin, and meso-zeaxanthin on cardiovascular inflammation and oxidative processes. Participants received either the active supplement or a placebo for six months.
We found significant reductions in key inflammatory markers and oxidized LDL in those taking the supplement. These results suggest that lutein and its companions may help combat inflammation, potentially contributing to healthier cardiovascular systems by supporting lower levels of harmful lipid oxidation.
We found significant reductions in key inflammatory markers and oxidized LDL in those taking the supplement. These results suggest that lutein and its companions may help combat inflammation, potentially contributing to healthier cardiovascular systems by supporting lower levels of harmful lipid oxidation.
7
We examined the link between serum carotenoids, including lutein, and mortality in patients with metabolic syndrome (MetS). Our study involved over 2,500 MetS patients and utilized advanced statistical methods to analyze data from multiple years.
We found that higher levels of certain carotenoids were generally protective against mortality, specifically linking lutein to lower death rates. However, this beneficial effect appeared reduced in patients taking lipid-lowering medications.
This suggests that incorporating carotenoid-rich foods could be especially important for MetS patients on such drugs.
We found that higher levels of certain carotenoids were generally protective against mortality, specifically linking lutein to lower death rates. However, this beneficial effect appeared reduced in patients taking lipid-lowering medications.
This suggests that incorporating carotenoid-rich foods could be especially important for MetS patients on such drugs.
8
We aimed to investigate how levels of certain carotenoids impact mortality rates in adults with metabolic dysfunction-associated fatty liver disease (MAFLD). Our analysis involved over 3,000 participants and focused on deaths from all causes, including cardiovascular issues.
Interestingly, higher levels of lutein and other carotenoids correlated with a lower risk of death. Specifically, those with the highest lutein levels were 38% less likely to die from cardiovascular disease compared to those with the lowest levels. However, it's important to note that while the correlation exists, we cannot definitively claim that lutein directly prevents heart disease based on this study alone.
Interestingly, higher levels of lutein and other carotenoids correlated with a lower risk of death. Specifically, those with the highest lutein levels were 38% less likely to die from cardiovascular disease compared to those with the lowest levels. However, it's important to note that while the correlation exists, we cannot definitively claim that lutein directly prevents heart disease based on this study alone.
References
- Sun L, He Z, Li Y, Huo Z, Liu L. The relationship between nutrient intake, lifestyle, and non-alcoholic fatty liver disease in patients with type 2 diabetes mellitus: Results from the National Health and Nutrition Examination Surveys 2007-2018. Clin Nutr ESPEN. 2025;66:446. 10.1016/j.clnesp.2025.02.008
- Li C, Liang Y, Lu Q, Lin Y, Wen S, et al. Protective effect of serum carotenoids on mortality among metabolic syndrome patients: attenuated by lipid-lowering drugs. Nutr J. 2025;24:27. 10.1186/s12937-025-01092-x
- Chen M, Cai S, Jia Q, Suo Y, Tang Y, et al. Inverse Relationship Between Serum Carotenoid Levels and Cardiovascular-Kidney-Metabolic Syndrome Among the General Adult Population. J Diabetes. 2025;17:e70046. 10.1111/1753-0407.70046
- Shi P, Sha Y, Wang X, Yang T, Wu J, et al. Targeted Delivery and ROS-Responsive Release of Lutein Nanoassemblies Inhibit Myocardial Ischemia-Reperfusion Injury by Improving Mitochondrial Function. Int J Nanomedicine. 2024;19:11973. 10.2147/IJN.S488532
- Lin B, Liu Z, Li D, Zhang T, Yu C. Associations of serum carotenoids with all-cause and cardiovascular mortality in adults with MAFLD. Nutr Metab Cardiovasc Dis. 2024;34:2315. 10.1016/j.numecd.2024.06.001
- Stringham NT, Green M, Roche W, Prado-Cabrero A, Mulcahy R, et al. Lutein, zeaxanthin, and meso-zeaxanthin supplementation attenuates inflammatory cytokines and markers of oxidative cardiovascular processes in humans. Nutr Metab Cardiovasc Dis. 2024;34:1976. 10.1016/j.numecd.2024.05.009
- Masle AM, Kibel A, Jukić I, Čičak P, Selthofer-Relatić K, et al. Enhancing Endothelial Function with Nutrient-Enriched Table Hen Eggs: A Randomized Study in Patients Recovering from Acute Coronary Syndrome. Clin Interv Aging. 2024;19:953. 10.2147/CIA.S461821
- Chen W, Li Y, Li M, Li H, Chen C, et al. Association between dietary carotenoid intakes and abdominal aortic calcification in adults: National Health and Nutrition Examination Survey 2013-2014. J Health Popul Nutr. 2024;43:20. 10.1186/s41043-024-00511-9
- Kolar L, Šušnjara P, Stupin M, Stupin A, Jukić I, et al. Enhanced Microvascular Adaptation to Acute Physical Stress and Reduced Oxidative Stress in Male Athletes Who Consumed Chicken Eggs Enriched with n-3 Polyunsaturated Fatty Acids and Antioxidants-Randomized Clinical Trial. Life (Basel). 2023;13. 10.3390/life13112140
- Ba W, Xu W, Deng Z, Zhang B, Zheng L, et al. The Antioxidant and Anti-Inflammatory Effects of the Main Carotenoids from Tomatoes via Nrf2 and NF-κB Signaling Pathways. Nutrients. 2023;15. 10.3390/nu15214652
- Wang M, Tang R, Zhou R, Qian Y, Di D. The protective effect of serum carotenoids on cardiovascular disease: a cross-sectional study from the general US adult population. Front Nutr. 2023;10:1154239. 10.3389/fnut.2023.1154239
- Šušnjara P, Mihaljević Z, Stupin A, Kolobarić N, Matić A, et al. Consumption of Nutritionally Enriched Hen Eggs Enhances Endothelium-Dependent Vasodilation via Cyclooxygenase Metabolites in Healthy Young People-A Randomized Study. Nutrients. 2023;15. 10.3390/nu15071599
- Zhu X, Cheang I, Tang Y, Shi M, Zhu Q, et al. Associations of Serum Carotenoids With Risk of All-Cause and Cardiovascular Mortality in Hypertensive Adults. J Am Heart Assoc. 2023;12:e027568. 10.1161/JAHA.122.027568
