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Doctor's Best Lutein with OptiLut
SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.3
USERS' SCORE
Good
Based on 11 Reviews
8.6
Supplement Facts
Serving Size: 2 Veggie Capsules
Amount Per Serving
%DV
Lutein (from 40mg OptiLut® lutein esters extracted from marigold flower, (Tagetes erecta))
20 mg
Trans-Zeaxanthin (from OptiLut® marigold flower ext., (Tagetes erecta))
2 mg

Top Medical Research Studies

8
Carotenoids linked to heart health
Inverse Relationship Between Serum Carotenoid Levels and Cardiovascular-Kidney-Metabolic Syndrome Among the General Adult Population.
High relevance to cardiovascular health
We explored the relationship between serum levels of carotenoids, like lutein, and cardiovascular-kidney-metabolic syndrome in over 1,600 U.S. adults. Through extensive analysis, we found that higher lutein levels corresponded with a lower likelihood of advanced CKM syndrome. Other carotenoids also showed similar protective effects, but β-cryptoxanthin did not demonstrate any significant benefit. This suggests that increasing intake of carotenoids, especially lutein, may be a smart choice for heart health.
Read More
8
Carotenoids linked to mortality risk
Associations of serum carotenoids with all-cause and cardiovascular mortality in adults with MAFLD.
Moderate relevance to heart health
We aimed to investigate how levels of certain carotenoids impact mortality rates in adults with metabolic dysfunction-associated fatty liver disease (MAFLD). Our analysis involved over 3,000 participants and focused on deaths from all causes, including cardiovascular issues.

Interestingly, higher levels of lutein and other carotenoids correlated with a lower risk of death. Specifically, those with the highest lutein levels were 38% less likely to die from cardiovascular disease compared to those with the lowest levels. However, it's important to note that while the correlation exists, we cannot definitively claim that lutein directly prevents heart disease based on this study alone.
Read More
8
Supplementation reduces inflammation markers
Lutein, zeaxanthin, and meso-zeaxanthin supplementation attenuates inflammatory cytokines and markers of oxidative cardiovascular processes in humans.
Strongly supports cardiovascular health
In our double-blind, placebo-controlled study, we assessed the effects of lutein, zeaxanthin, and meso-zeaxanthin on cardiovascular inflammation and oxidative processes. Participants received either the active supplement or a placebo for six months.

We found significant reductions in key inflammatory markers and oxidized LDL in those taking the supplement. These results suggest that lutein and its companions may help combat inflammation, potentially contributing to healthier cardiovascular systems by supporting lower levels of harmful lipid oxidation.
Read More

Most Useful Reviews

8.8
Eased eye strain
Due to severe dry eye and presbyopia, I struggled to read small letters, particularly at morning. After taking lutein, I noticed a significant reduction in discomfort, and clearer vision emerged soon after. Initially sceptical, I was pleasantly surprised as eye strain symptoms eased, allowing me to read effortlessly. This supplement has made a noticeable difference in my day-to-day activities, leading me to commit to its ongoing use. I’m grateful for finding this wonderful product.
Read More
9.5
Improved eye health
Since incorporating Lutein into my routine, my eye health has substantially improved. Symptoms of dryness have decreased, and the light sensitivity I previously experienced has lessened. This supplement plays a crucial role in preventing potential eye diseases. I believe it’s essential for anyone concerned about maintaining their eyesight to consider Lutein.
Read More
9.5
Reduced eye aging
Since I began taking this product, focusing my eyes has become much easier. Lutein is prevalent in the macula and crystalline lens; a deficiency can lead to eye aging, such as macular degeneration and cataracts. As an antioxidant, lutein combats "active oxygen," which accelerates eye aging, absorbing harmful light and providing protection. It's recommended to take at least 6 mg daily, with a continuous intake of 10 mg reducing the risk of age-related eye diseases. Although it's late for treating my current condition, I will continue to purchase it.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 13 Researches
7.3
  • All Researches
9
Lutein improves mitochondrial function
Targeted Delivery and ROS-Responsive Release of Lutein Nanoassemblies Inhibit Myocardial Ischemia-Reperfusion Injury by Improving Mitochondrial Function.
Highly relevant based on study design
We explored the potential of lutein, a powerful antioxidant, in treating myocardial ischemia-reperfusion injury. To enhance its effectiveness, a novel delivery system named lutein@DTPP was developed, allowing for targeted administration directly to heart tissues.

Our findings showed that this method improved mitochondrial function in heart cells, crucial for reducing damage and preventing cell death. However, while lutein demonstrated benefits in this context, it's important to note that the study primarily focused on a specific injury model, and broader effects on cardiovascular disease might still require more investigation.
Read More
8
Carotenoids linked to heart health
Inverse Relationship Between Serum Carotenoid Levels and Cardiovascular-Kidney-Metabolic Syndrome Among the General Adult Population.
High relevance to cardiovascular health
We explored the relationship between serum levels of carotenoids, like lutein, and cardiovascular-kidney-metabolic syndrome in over 1,600 U.S. adults. Through extensive analysis, we found that higher lutein levels corresponded with a lower likelihood of advanced CKM syndrome. Other carotenoids also showed similar protective effects, but β-cryptoxanthin did not demonstrate any significant benefit. This suggests that increasing intake of carotenoids, especially lutein, may be a smart choice for heart health.
Read More
8
Carotenoids linked to mortality risk
Associations of serum carotenoids with all-cause and cardiovascular mortality in adults with MAFLD.
Moderate relevance to heart health
We aimed to investigate how levels of certain carotenoids impact mortality rates in adults with metabolic dysfunction-associated fatty liver disease (MAFLD). Our analysis involved over 3,000 participants and focused on deaths from all causes, including cardiovascular issues.

Interestingly, higher levels of lutein and other carotenoids correlated with a lower risk of death. Specifically, those with the highest lutein levels were 38% less likely to die from cardiovascular disease compared to those with the lowest levels. However, it's important to note that while the correlation exists, we cannot definitively claim that lutein directly prevents heart disease based on this study alone.
Read More
8
Supplementation reduces inflammation markers
Lutein, zeaxanthin, and meso-zeaxanthin supplementation attenuates inflammatory cytokines and markers of oxidative cardiovascular processes in humans.
Strongly supports cardiovascular health
In our double-blind, placebo-controlled study, we assessed the effects of lutein, zeaxanthin, and meso-zeaxanthin on cardiovascular inflammation and oxidative processes. Participants received either the active supplement or a placebo for six months.

We found significant reductions in key inflammatory markers and oxidized LDL in those taking the supplement. These results suggest that lutein and its companions may help combat inflammation, potentially contributing to healthier cardiovascular systems by supporting lower levels of harmful lipid oxidation.
Read More
8
Carotenoid intake reduces AAC risk
Association between dietary carotenoid intakes and abdominal aortic calcification in adults: National Health and Nutrition Examination Survey 2013-2014.
Study highly relevant to cardiovascular health
Our analysis focused on how carotenoid intake relates to abdominal aortic calcification (AAC), a crucial indicator of cardiovascular risk. In a study with 2,889 participants, we found that increased consumption of carotenoids—particularly lutein and zeaxanthin—was linked to a reduced risk of severe AAC.

Results showed that higher intakes of various carotenoids, including lutein, significantly lowered the odds of AAC, emphasizing the potential heart health benefits of these nutrients. This suggests that including more carotenoid-rich foods in our diet might be beneficial for our cardiovascular health.
Read More

User Reviews

USERS' SCORE
Good
Based on 11 Reviews
8.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
8.8
Eased eye strain
Due to severe dry eye and presbyopia, I struggled to read small letters, particularly at morning. After taking lutein, I noticed a significant reduction in discomfort, and clearer vision emerged soon after. Initially sceptical, I was pleasantly surprised as eye strain symptoms eased, allowing me to read effortlessly. This supplement has made a noticeable difference in my day-to-day activities, leading me to commit to its ongoing use. I’m grateful for finding this wonderful product.
Read More
9.5
Improved eye health
Since incorporating Lutein into my routine, my eye health has substantially improved. Symptoms of dryness have decreased, and the light sensitivity I previously experienced has lessened. This supplement plays a crucial role in preventing potential eye diseases. I believe it’s essential for anyone concerned about maintaining their eyesight to consider Lutein.
Read More
9.5
Reduced eye aging
Since I began taking this product, focusing my eyes has become much easier. Lutein is prevalent in the macula and crystalline lens; a deficiency can lead to eye aging, such as macular degeneration and cataracts. As an antioxidant, lutein combats "active oxygen," which accelerates eye aging, absorbing harmful light and providing protection. It's recommended to take at least 6 mg daily, with a continuous intake of 10 mg reducing the risk of age-related eye diseases. Although it's late for treating my current condition, I will continue to purchase it.
Read More
8.8
Stabilised retinal condition
My mother, aged over 65, has lived with retinal dystrophy for many years. She consistently takes Lutein for her eyesight, reportedly achieving better twilight vision, colour distinction, and overall eye comfort. We consume 30-40 mg daily to halt disease progression, as she claims her eyes feel less strained, and her mind feels clearer in the mornings. This natural carotenoid has proven essential, thus we remain committed to its use, hoping it will help prolong her vision health. Eye health matters immensely and should not be neglected.
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7.5
Recommending for prevention
The quality of this lutein product is commendable, and I will repurchase it if needed. This carotenoid helps enhance dark adaptation, filters harmful blue light, and improves overall visual function. Its protective properties support prevention against macular degeneration and cataracts, making it an essential supplement for eye health. Importantly, it also contributes to reducing the risk of cardiovascular disease, making it beneficial for overall wellbeing.
Read More
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